Cytisine, also known as baptitoxine and sophorine, is an alkaloid that occurs naturally in several plant genera. In this trial in New Zealand, cytisine was superior to nicotine-replacement therapy in helping smokers quit. The findings are summarized in the NEJM video. Cytisine was first marketed in Bulgaria in 1964 (called Tabex) and then became widely available in other European countries.
Read the full NEJM Original Article: http://www.nejm.org/doi/full/10.1056/NEJMoa1407764
Related reading:
Quitting smoking: Still a challenge, but newer tools show promise - CCJM http://buff.ly/1xCK2fP
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